Pay in 4 interest-free payments of $111.25 Learn more
Ships within 48 hours · Estimated delivery Sep 13 - Sep 18
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
Product Name 5(6)-ROX PEG3 azide Synonyms 5-(and 6)-Carboxy-X-rhodamine PEG3 Azide CAS Number N/A Related CAS Molecular Formula C41H46N6O7 Molecular Weight 734
Product Name MaP555-Maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C33H34N6O7S Molecular Weight 658
CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C56H90N10O20 Molecular Weight 1223
Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Molecular Glues for Targeted ProteinSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
US$ 130.00
US$ 130.00
US$ 50.00
US$ 80.00
US$ 190.00
US$ 50.00
